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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044400Generated: October 31, 2026

Methanol → HCID 46910989, compound

https://huagongshe.com/reaction/1044400

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
Reactant1,4-Dioxane hydrochlorideHCID 20443148—
ReactantHCID 58580200HCID 58580200—
SolventDichloromethaneHCID 6344—
ProductHCID 46910989HCID 46910989—

Reaction Steps

To a solution of 4-((4-fluorophenylthio)methyl)-1-(3-methoxy-4-((2-(trimethylsilyl)ethoxy)methoxy)phenyl)pyridin-2(1H)-one Part A (64 mg, 0.13 mmol) in CH2Cl2 (1.0 mL) and MeOH (1.0 mL) was added 4M HCl/Dioxane (2 mL, 8M mmol). After stirring at RT for 2 h, concentration under vacuum provided the crude phenol as a white solid. LC-MS, [M+H]+=358.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563583B2
Source datasetuspto-grants-2013_10
ORD IDord-3e93bdc9b3f6421a936cb3cf88a9b1dc
Source noteuspto-grants-2013_10