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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044541Generated: October 30, 2026

N-{[7-Amino-8-(3,4-dichlorobenzyl)-5,6,7,8-tetrahydronaphthalen-2-yl]methyl}propane-1-sulfonamide hydrochloride → Methanesulfonic acid 1-(propane-1-sulfonyl)-azetidin-3-ylmethyl ester

https://huagongshe.com/reaction/1044541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-{[7-Amino-8-(3,4-dichlorobenzyl)-5,6,7,8-tetrahydronaphthalen-2-yl]methyl}propane-1-sulfonamide hydrochlorideHCID 57467213—
Reactant[1-(Propane-1-sulfonyl)-azetidin-3-yl]methanolHCID 59547792—
ProductMethanesulfonic acid 1-(propane-1-sulfonyl)-azetidin-3-ylmethyl esterHCID 57476714—

Reaction Steps

Prepared by standard procedure from [1-(propane-1-sulfonyl)-azetidin-3-yl]methanol and methan-1-sulfonyl chloride (e.g. example 40)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563617B2
Source datasetuspto-grants-2013_10
ORD IDord-505c03fc9eac4cd38f9ec6fcf0b52193
Source noteuspto-grants-2013_10