Iodoethane → 2-(Butyloxy)-9-[5-(1-ethyl-3-piperidinyl)pentyl]-8-(methyloxy)-9H-purin-6-amine
Reaction equation
C(N1[CH2:8][CH2:7][CH2:6][CH:5]([CH2:9][CH2:10][N:11]2[C:19]([O:20][CH3:21])=[N:18][C:17]3[C:12]2=[N:13][C:14]([O:23][C@@H:24](C)[CH2:25][CH2:26][CH3:27])=[N:15][C:16]=3[NH2:22])C1)C.C(OC1N=[C:41]2[C:37](N=[C:39](OC)[N:40]2[CH2:43][CH2:44]CCCC2CCCNC2)=[C:36](N)N=1)CCC.ICC>>[CH2:24]([O:23][C:14]1[N:13]=[C:12]2[C:17]([N:18]=[C:19]([O:20][CH3:21])[N:11]2[CH2:10][CH2:9][CH2:5][CH2:6][CH2:7][CH:8]2[CH2:36][CH2:37][CH2:41][N:40]([CH2:43][CH3:44])[CH2:39]2)=[C:16]([NH2:22])[N:15]=1)[CH2:25][CH2:26][CH3:27]Participants
4
Reactant 3
Product 1
Procedure
Prepared similarly to Intermediate 46 from 2-(butyloxy)-8-(methyloxy)-9-[5-(3-piperidinyl)pentyl]-9H-purin-6-amine and 2-iodoethane.
Sources & evidence
- ORD record
- ord-64da4dc494ee4bcf93f02b1a98d364af
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08563717B2
Reaction notes
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