Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044915Generated: November 1, 2026

Benzyl 4-(3-bromopropyl)piperidine-1-carboxylate → Phenylmethyl 4-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylate

https://huagongshe.com/reaction/1044915

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl 4-(3-bromopropyl)piperidine-1-carboxylateHCID 10980720—
ReactantPhenylmethyl 2-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306132—
ReactantHCID 178450370HCID 178450370—
ProductPhenylmethyl 4-{3-[6-amino-2-(butyloxy)-8-(methyloxy)-9H-purin-9-yl]propyl}-1-piperidinecarboxylateHCID 58306243—

Reaction Steps

Prepared similarly to Intermediate 31 from 2-(butyloxy)-8-(methyloxy)-9H-purin-6-amine trifluoroacetate and phenylmethyl 4-(3-bromopropyl)-1-piperidinecarboxylate. LCMS (System D): tRET=3.39 min; MH+ 497

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-2e417b6565624676be96a0ce57c51839
Source noteuspto-grants-2013_10