Iodoethane → 9-[4-(1-Ethyl-4-piperidinyl)butyl]-2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9H-purin-6-amine

HRID 1044925Notes

Reaction equation

HRID 1044925 reaction equation
C(N1[CH2:8][CH2:7][CH2:6][CH:5]([CH2:9][CH2:10][N:11]2[C:19]([O:20][CH3:21])=[N:18][C:17]3[C:12]2=[N:13][C:14]([O:23][C@@H:24]([CH3:28])[CH2:25][CH2:26][CH3:27])=[N:15][C:16]=3[NH2:22])C1)C.C[C@H](OC1N=[C:42]2[C:38](N=[C:40](OC)[N:41]2[CH2:44][CH2:45]CCC2CCNCC2)=C(N)N=1)CCC.ICC>>[CH2:42]([N:41]1[CH2:40][CH2:8][CH:7]([CH2:6][CH2:5][CH2:9][CH2:10][N:11]2[C:19]([O:20][CH3:21])=[N:18][C:17]3[C:12]2=[N:13][C:14]([O:23][C@@H:24]([CH3:28])[CH2:25][CH2:26][CH3:27])=[N:15][C:16]=3[NH2:22])[CH2:45][CH2:44]1)[CH3:38]

Participants

4

Procedure

Prepared similarly to Intermediate 46 from 2-{[(1S)-1-methylbutyl]oxy}-8-(methyloxy)-9-[4-(4-piperidinyl)butyl]-9H-purin-6-amine and 2-iodoethane.

Sources & evidence

ORD record
ord-200a26c182da4c78865117d1562578f1
Source dataset
uspto-grants-2013_10
Patent number
US08563717B2

Reaction notes

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