Iodoethane → N2-Butyl-9-[4-(1-ethyl-4-piperidinyl)butyl]-8-(methyloxy)-9H-purine-2,6-diamine

HRID 1044928Notes

Reaction equation

HRID 1044928 reaction equation
[CH2:1](N1CCCC(CCN2C(OC)=NC3C2=NC(O[C@@H](C)CCC)=NC=3N)C1)[CH3:2].[CH2:29]([NH:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:53][CH3:54])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH:47]2[CH2:52][CH2:51][NH:50][CH2:49][CH2:48]2)=[C:36]([NH2:55])[N:35]=1)[CH2:30][CH2:31][CH3:32].ICC>>[CH2:29]([NH:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:53][CH3:54])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH:47]2[CH2:48][CH2:49][N:50]([CH2:1][CH3:2])[CH2:51][CH2:52]2)=[C:36]([NH2:55])[N:35]=1)[CH2:30][CH2:31][CH3:32]

Participants

4

Procedure

Prepared similarly to Intermediate 46 from N2-butyl-8-(methyloxy)-9-[4-(4-piperidinyl)butyl]-9H-purine-2,6-diamine and 2-iodoethane.

Sources & evidence

ORD record
ord-449e2decb01249e3b600dff2b26d0a88
Source dataset
uspto-grants-2013_10
Patent number
US08563717B2

Reaction notes

Loading…