Iodoethane → 2-(Butyloxy)-9-[6-(1-ethyl-4-piperidinyl)hexyl]-8-(methyloxy)-9H-purin-6-amine
Reaction equation
[CH2:1](N1CCCC(CCN2C(OC)=NC3C2=NC(O[C@@H](C)CCC)=NC=3N)C1)[CH3:2].[CH2:29]([O:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:55][CH3:56])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH:49]2[CH2:54][CH2:53][NH:52][CH2:51][CH2:50]2)=[C:36]([NH2:57])[N:35]=1)[CH2:30][CH2:31][CH3:32].ICC>>[CH2:29]([O:33][C:34]1[N:42]=[C:41]2[C:37]([N:38]=[C:39]([O:55][CH3:56])[N:40]2[CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH:49]2[CH2:50][CH2:51][N:52]([CH2:1][CH3:2])[CH2:53][CH2:54]2)=[C:36]([NH2:57])[N:35]=1)[CH2:30][CH2:31][CH3:32]Participants
4
Reactant 3
Product 1
Procedure
Prepared similarly to Intermediate 46 from 2-(butyloxy)-8-(methyloxy)-9-[6-(4-piperidinyl)hexyl]-9H-purin-6-amine and 2-iodoethane.
Sources & evidence
- ORD record
- ord-a7f093ae5a734c1d94356f34389275c7
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08563717B2
Reaction notes
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