HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 67043412, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 1197362-78-9 | HCID 67043323 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 67043412 | HCID 67043412 | — |
Reaction Steps
3.02 g of 7-fluoro-1,2-benzisothiazol-3(2H)-one 1,1-dioxide (EP291851 A2 19881123), 1.64 ml of thionyl chloride and a catalytic amount of DMF in 13 ml of dioxane are heated under reflux for 45 hours. The mixture is concentrated and the residue is crystallized in toluene. 2.50 g of a crude solid is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563744B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-869dec3189574e918d0be4123a0eb1d1 |
| Source note | uspto-grants-2013_10 |