Piperazine → Benzoic acid, 2-bromo-4-(1-piperazinyl)-, methyl ester

HRID 1045144Notes

Reaction equation

HRID 1045144 reaction equation
[NH:1]1[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[Br:7][C:8]1[CH:17]=[C:16](F)[CH:15]=[CH:14][C:9]=1[C:10]([O:12][CH3:13])=[O:11]>>[Br:7][C:8]1[CH:17]=[C:16]([N:1]2[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]2)[CH:15]=[CH:14][C:9]=1[C:10]([O:12][CH3:13])=[O:11]

Participants

3

Reactant 2

HCID 4837PiperazineHCID 7210837Methyl 2-bromo-4-fluorobenzoate

Product 1

HCID 67227310Benzoic acid, 2-bromo-4-(1-piperazinyl)-, methyl ester

Procedure

This example was prepared by substituting piperazine for EXAMPLE 1B and methyl 2-bromo-4-fluorobenzoate for EXAMPLE 1C in EXAMPLE 1D.

Sources & evidence

ORD record
ord-5d3d88224dd64e10ac8f76cd570e417c
Source dataset
uspto-grants-2013_10
Patent number
US08563735B2

Reaction notes

Loading…