Hydrochloric Acid → 2-Amino-3,4-dihydronaphthalen-1(2H)-one--hydrogen chloride (1/1)

Participants

Reaction Conditions

Reaction Steps

N-(1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)-acetamide (16.5 g, 81 mmol) was added to 3N aqueous hydrochloric acid (270 ml) and stirred at 100° C. for 5 hours. After removal of the solvent, the precipitate was filtered, washed with ethanol, and dried to give 2-amino-3,4-dihydro-2H-naphthalen-1-one hydrochloride (16.0 g, 81 mmol, 100%) as white crystals.

Provenance & Evidence