HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-chloro-2-oxopropanoate → 2-(7-Nitro-1H-indol-2-yl)-thiazole-4-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-chloro-2-oxopropanoate | HCID 12530121 | — |
| Reactant | 7-nitro-1H-indole-2-carbothioamide | HCID 57901866 | — |
| Product | 2-(7-Nitro-1H-indol-2-yl)-thiazole-4-carboxylic acid methyl ester | HCID 136337200 | — |
Reaction Steps
3-Chloro-2-oxo-propionic acid methyl ester and 7-nitro-1H-indole-2-carbothioic acid amide prepared in Step A of Preparation 110 were reacted according to the same procedure as Preparation 110 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569307B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-e5b63f360e7a4bf096747d2247f42503 |
| Source note | uspto-grants-2013_10 |