Tert-Butylamine → 6-bromo-N-tert-butylnicotinamide

HRID 1046224Notes

Reaction equation

[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][N:3]=1.[C:11]([NH2:15])([CH3:14])([CH3:13])[CH3:12]>>[Br:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([NH:15][C:11]([CH3:14])([CH3:13])[CH3:12])=[O:7])=[CH:4][N:3]=1

Participants

Reactant 2

HCID 6385Tert-Butylamine

HCID 234995286-Bromonicotinoyl chloride

Product 1

HCID 664644386-bromo-N-tert-butylnicotinamide

Procedure

6-bromo-N-tert-butylnicotinamide was prepared from 6-bromonicotinoyl chloride and tert-butylamine.

Sources & evidence

ORD record: ord-6e13443a9d4243539858c38dfbf197f6
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08569292B2

Reaction notes

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