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HRID1047105

反应详情

EQUATION

反应方程式

HRID 1047105 的结构方程式

REACTANTS

反应物

2
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：O=C1C[C@@H](c2ccccc2)c2ccc(Cl)cc21
HCID11997855

未命名化合物

PRODUCTS

生成物

1
结构：O[C@H]1C[C@@H](c2ccccc2)c2ccc(Cl)cc21
HCID11521607

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

(S)-6-chloro-3-phenylindan-1-one (IVa) can by reduced with sodium borohydride adapting a method described in Bøgesø J. Med. Chem. 1983, 26, 935, using ethanol as solvent and performing the reaction at approximately 0° C., giving compound (Va).

WORKUP

后处理

  1. customthe reaction at approximately 0° C.
  2. customgiving compound (Va)