Hydrochloric Acid → HCID 69621152, compound

Participants

Reaction Steps

To a solution of (R)-ethyl 1-(1-(tert-butoxycarbonyl)piperidin-3-yl)-6-(6-(3-ethylureido)-4-(4-(trifluoromethyl)thiazol-2-yl)pyridin-3-yl)-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate (300 mg) in dioxane (3 mL) was added 4 N HCl in dioxane (2 eq). The reaction mixture was stirred at room temperature overnight and the solid that formed was collected by filtration to provide the desired product.

Provenance & Evidence