HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 14435731, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Isovaleryl chloride | HCID 66054 | — |
| Reactant | Morpholine, 4-(1-cyclohexen-1-yl)- | HCID 69589 | — |
| Product | HCID 14435731 | HCID 14435731 | 90% |
Reaction Steps
Compound IVd is obtained in 90% yield as a pale yellow liquid, according to Example 4, from 4-cyclohex-1-enyl-morpholine (82.64 g, 0.5 mol, obtained in Example 1), triethylamine (71.34 g, 0.71 mol), isovaleryl chloride (85.01 g, 0.71 mol), toluene (760 mL) and 20% aqueous HCl (166 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569518B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-8da7be3a70904bd09b519bf4ec836425 |
| Source note | uspto-grants-2013_10 |