Dimethylformamide → HCID 136350271, compound

HRID 1047460Notes

Reaction equation

HRID 1047460 reaction equation
[NH2:1][C:2]1[NH:3][C:4](=[O:20])[C:5]2[N:6]=[CH:7][N:8]([CH:11]3[CH2:15][CH:14]([OH:16])[CH:13]([CH2:17][OH:18])[C:12]3=[CH2:19])[C:9]=2[N:10]=1.[CH3:21][N:22]([CH3:25])[CH:23]=[O:24]>>[CH3:21][N:22]([CH3:25])[CH:23]=[O:24].[NH2:1][C:2]1[NH:3][C:4](=[O:20])[C:5]2[N:6]=[CH:7][N:8]([CH:11]3[CH2:15][CH:14]([OH:16])[CH:13]([CH2:17][OH:18])[C:12]3=[CH2:19])[C:9]=2[N:10]=1

Participants

3

Reactant 2

HCID 6228DimethylformamideHCID 135605572HCID 135605572, compound

Product 1

HCID 136350271HCID 136350271, compoundYield 85.6%

Conditions

Temperature
0 °C

Procedure

The compound obtained in Example 1-9 (1 g) was added to N,N-dimethylformamide (5 ml) and stirred at room temperature for 2 hrs and at 0° C. for 1 hr. The resulting solution was filtered to obtain the title compound as a white-colored solid (0.95 g, yield: 85.6%).

Workup

  1. filtrationThe resulting solution was filtered

Sources & evidence

ORD record
ord-f73ca6d6c3114e8d9172899b98867da5
Source dataset
uspto-grants-2013_10
Patent number
US08569491B2

Reaction notes

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