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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1047953Generated: November 2, 2026

3,6-Difluorophthalic acid → 2-Amino-4,7-difluoro-indan-2-carboxylic acid ethyl ester HCl salt

https://huagongshe.com/reaction/1047953

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,6-Difluorophthalic acidHCID 643385—
Reactant2-amino-4,5-difluoro-indan-2-carboxylic acid ethyl ester HCl saltHCID 68589642—
Product2-Amino-4,7-difluoro-indan-2-carboxylic acid ethyl ester HCl saltHCID 68590994—

Reaction Steps

2-Amino-4,7-difluoro-indan-2-carboxylic acid ethyl ester HCl salt was prepared from 3,6-difluoro-phthalic acid as indicated by the scheme above regarding A7-D7 utilizing the same procedures as for the synthesis of 2-amino-4,5-difluoro-indan-2-carboxylic acid ethyl ester HCl salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08569535B2
Source datasetuspto-grants-2013_10
ORD IDord-316a2a5446b74a879cbd8e1e5eac5830
Source noteuspto-grants-2013_10