反应详情

To a stirred suspension of 2-(aminomethyl)phenol, (4.0 g, 32.5 mmol) in ethanol (65 mL) was added 4-chlorobenzaldehyde (3.86 mL, 32.8 mmol). The resulting reaction mixture was stirred at rt for 3 h. The solvent was removed and 100 ml of toluene was added and concentrated in vacuum twice. The resulting imine was dried under vacuum overnight and used in the next step without further purification.

1. customThe resulting reaction mixture
2. customThe solvent was removed
3. addition100 ml of toluene was added
4. concentrationconcentrated in vacuum twice
5. dry with materialThe resulting imine was dried under vacuum overnight
6. customused in the next step without further purification