Dichloromethane → 2-Benzoyloxymethyl-5-[(6,2'-dimethyl-4'-propionylbiphenyl-3-ylamino)methyl]benzyl benzoate

HRID 104862Notes

Reaction equation

HRID 104862 reaction equation
[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[O:9][CH2:10][c:11]1[c:12]([CH2:44][O:45][C:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)=[O:53])[cH:13][cH:14][c:15]([CH2:17][N:18]([c:19]2[cH:20][c:21](-[c:26]3[c:27]([CH3:36])[cH:28][c:29]([C:32]([CH2:33][CH3:34])=[O:35])[cH:30][cH:31]3)[c:22]([CH3:25])[cH:23][cH:24]2)[C:37]([O:38][C:39]([CH3:40])([CH3:41])[CH3:42])=[O:43])[cH:16]1.[Cl:61][CH2:62][Cl:63].[OH:54][C:55]([C:56]([F:57])([F:58])[F:59])=[O:60]>>[C:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)(=[O:8])[O:9][CH2:10][c:11]1[c:12]([CH2:44][O:45][C:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)=[O:53])[cH:13][cH:14][c:15]([CH2:17][NH:18][c:19]2[cH:20][c:21](-[c:26]3[c:27]([CH3:36])[cH:28][c:29]([C:32]([CH2:33][CH3:34])=[O:35])[cH:30][cH:31]3)[c:22]([CH3:25])[cH:23][cH:24]2)[cH:16]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 697928892-Benzoyloxymethyl-5-{[tert-butoxycarbonyl(6,2'-dimethyl-4'-propionyl-biphenyl-3-yl)amino]methyl}benzyl benzoate

Product 1

HCID 697926032-Benzoyloxymethyl-5-[(6,2'-dimethyl-4'-propionylbiphenyl-3-ylamino)methyl]benzyl benzoate

Sources & evidence

ORD record
ord-b073fcc00df6499b849d835a6871230a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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