HCID 23134613, compound → 3-Ethoxy-2-methylaniline

HRID 1048631Notes

Reaction equation

HRID 1048631 reaction equation
[CH2:1]([O:3][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([N+:10]([O-])=O)[C:5]=1[CH3:13])[CH3:2]>[C].[Pd].C(O)C>[CH2:1]([O:3][C:4]1[C:5]([CH3:13])=[C:6]([CH:7]=[CH:8][CH:9]=1)[NH2:10])[CH3:2]

Participants

4

Reactant 1

HCID 23134613HCID 23134613, compound

Product 1

HCID 137370113-Ethoxy-2-methylaniline

Reagents, catalysts & solvents 2

HCID 178418390HCID 178418390, compoundCatalystHCID 702EthanolSolvent

Procedure

A mixture of 1-ethoxy-2-methyl-3-nitrobenzene described in Reference Preparation example 2539.9 g, palladium-carbon (palladium 5%) 4 g and ethanol 200 mL was stirred at room temperature under hydrogen atmosphere for eighteen hours. The mixtures were filtered and the filtrates were concentrated to give 3-ethoxy-2-methylaniline 33.0 g.

Workup

  1. filtrationThe mixtures were filtered
  2. concentrationthe filtrates were concentrated

Sources & evidence

ORD record
ord-0124a7c0ff9a437f91fc0767421e3bb0
Source dataset
uspto-grants-2016_07
Patent number
US09380782B2

Reaction notes

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