1-Butanol → tert-butyl 2-[[5-bromo-4-[3-[(2-methylpropan-2-yl)oxycarbonylamino]piperidin-1-yl]-1H-pyrrolo[2,3-b]pyridin-3-yl]carbamoyl]morpholine-4-carboxylate
Reaction equation
[Br:1][c:2]1[c:3]([F:27])[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12](=[O:13])[CH:14]1[O:15][CH2:16][CH2:17][N:18]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:19]1.[CH2:51]([OH:52])[CH2:53][CH2:54][CH3:55].[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[NH:28]1[CH2:29][CH:30]([NH:34][C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[CH2:31][CH2:32][CH2:33]1>>[Br:1][c:2]1[c:3]([N:28]2[CH2:29][CH:30]([NH:34][C:35]([O:36][C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[CH2:31][CH2:32][CH2:33]2)[c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[NH:11][C:12](=[O:13])[CH:14]1[O:15][CH2:16][CH2:17][N:18]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:19]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-91e9e24151944c48b67d311115634a7b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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