HCID 117759626, compound → HCID 117759852, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-(3-ethoxy-3-oxopropyl)-2-methylpyridine 1-oxide (1.99 g) and acetic anhydride (10 mL) was stirred at 100° C. for 30 min. The solvent was evaporated under reduced pressure and the residue was purified by silica gel column chromatography (NH, ethyl acetate/hexane) to give a crude product of the title compound as a colorless oil. This compound was used for the next step without further purification.

Provenance & Evidence