反应详情

To a solution of 5-(benzyloxy)-2-(2-fluoro-5-methoxyphenyl)-3-neopentylpyridine (2.95 g) in ethyl acetate (50 mL) was added 10% palladium-carbon (628 mg) and, under a hydrogen atmosphere, the mixture was stirred at room temperature for 20 min. The catalyst was filtered and the filtrate was concentrated to give the title compound (2.26 g) as a white solid.

1. filtrationThe catalyst was filtered
2. concentrationthe filtrate was concentrated