HCID 131736022, compound → HCID 117759663, compound

Participants

Reaction Steps

Under a hydrogen atmosphere, a mixture of ethyl 3-(3-(2-fluoro-2-(5-(2-fluoro-5-methoxyphenyl)-6-neopentylpyridin-2-yl)ethyl)phenyl)acrylate (119 mg), 10% palladium-carbon (50 mg) and ethyl acetate (2.0 mL) was stirred at room temperature for 1 hr. The catalyst was removed by filtration, and the filtrate was evaporated under reduced pressure to give the title compound (90 mg) as a colorless oil.

Provenance & Evidence