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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1049535Generated: October 30, 2026

Sodium Hydroxide → HCID 117759797, compound

https://huagongshe.com/reaction/1049535

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 117759663HCID 117759663—
SolventMethanolHCID 887—
SolventTetrahydrofuranHCID 8028—
ProductHCID 117759797HCID 117759797—

Reaction Steps

To a solution of ethyl 3-(3-(2-fluoro-2-(5-(2-fluoro-5-methoxyphenyl)-6-neopentylpyridin-2-yl)ethyl)phenyl)propanoate (90 mg) in THF (2.0 mL) and methanol (1.0 mL) was added 1N aqueous sodium hydroxide solution (2.0 mL), and the mixture was stirred at room temperature for 30 min. To the reaction mixture was added, at room temperature, 1N hydrochloric acid (2.0 mL), and the mixture was extracted with ethyl acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09382188B2
Source datasetuspto-grants-2016_07
ORD IDord-40d61dd1b0434f278b96ba8902e25041
Source noteuspto-grants-2016_07