Lawesson's reagent → HCID 117760193, compound

Participants

Reaction Steps

A solution of 2′-fluoro-5′-methoxy-2-(2-pivaloylhydrazinecarbonyl)-[1,1′-biphenyl]-4-yl pivalate (203 mg) and the Lawesson's reagent (194 mg) in THF (6.0 mL) was stirred at 80° C. for 50 min. The reaction mixture was concentrated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (196 mg) as a colorless oil.

Provenance & Evidence