Hydrochloric Acid → HCID 117760095, compound

Participants

Reaction Steps

To a solution of tert-butyl 2′-fluoro-5′-methoxy-2-(3-methoxy-3-methylbutyl)biphenyl-4-yl carbonate (199 mg) in ethyl acetate (5 mL) was added a solution (4 M, 2 mL) of hydrogen chloride in ethyl acetate, and the mixture was stirred at room temperature for 20 hr. The solvent was evaporated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (203 mg) as a colorless oil.

Provenance & Evidence