HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-methyl-1H-imidazole-2-carboxylic acid → HCID 117699159, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-methyl-1H-imidazole-2-carboxylic acid | HCID 557678 | — |
| Reactant | 1-Methyl-1H-imidazole-2-carbonyl chloride | HCID 22646752 | — |
| Reactant | 5-(4-Aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione | HCID 117699167 | — |
| Product | HCID 117699159 | HCID 117699159 | 13.4% |
Reaction Steps
1-Methyl-1H-imidazole-2-carboxylic acid (40 mg, 0.317 mmol) was made into acid chloride in a conventional manner. By using 5-(4-aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione (50 mg, 0.158 mmol) obtained in Example 1, (3), and 1-methyl-1H-imidazole-2-carboxylic acid chloride mentioned above, the title compound (9 mg, yield 13%) was obtained in the same manner as that of Example 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382236B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-2ae9133a1f0840bfb760ee362ebd0d36 |
| Source note | uspto-grants-2016_07 |