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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1049801Generated: October 31, 2026

Methyl iodide → HCID 117699197, compound

https://huagongshe.com/reaction/1049801

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl iodideHCID 6328—
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 117699078HCID 117699078—
ProductHCID 117699197HCID 11769919773%

Reaction Steps

By using 3-bromo-N-[4-(2,4-dioxo-1,2,3,4-tetrahydronaphtho[1,2-b][1,4]diazepin-5-yl)phenyl]benzenesulfonamide (78 mg, 0.145 mmol) obtained in Example 147, potassium carbonate (22 mg, 0.159 mmol), and methyl iodide (11 μL, 0.177 mmol), the title compound (58 mg, yield 73%) was obtained in the same manner as that of Example 152.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09382236B2
Source datasetuspto-grants-2016_07
ORD IDord-c188110f16c84c88ab09d369f61dafd2
Source noteuspto-grants-2016_07