HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-5-fluoro-7H-pyrrolo(2,3-d)pyrimidine → 6-[(5-Fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-5-methoxy-1,3-benzothiazol-2(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-5-fluoro-7H-pyrrolo(2,3-d)pyrimidine | HCID 11321224 | — |
| Reactant | 6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one | HCID 90014948 | — |
| Product | 6-[(5-Fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-5-methoxy-1,3-benzothiazol-2(3H)-one | HCID 73388370 | — |
Reaction Steps
50 mg (291 μmol) 4-chloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine (CAS-No: 582313-57-3) were transformed in analogy to example 1 using 6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one to give after working up and purification 2.9 mg (3%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382255B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-9011cf2eb98f4997884899a978a36326 |
| Source note | uspto-grants-2016_07 |