Acetic Acid → HCID 178513510, compound

Participants

Reaction Steps

1H-Pyrazole-3-carboxylic acid (3-carbamoyl-thiophen-2-yl)-amide (355 mg, 1.5 mmol) is mixed with AcOH (5 mL). NBS (280 mg, 1.58 mmol) is then added and the mixture is stirred at room temperature overnight. Evaporation gives a residue that is subsequently dissolved in DCM, the resulting organic phase is washed with aqueous NaHCO3, dried over MgSO4, filtered and evaporated to give a residue that is used as such.

Provenance & Evidence