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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1049968Generated: October 30, 2026

Hydrochloric Acid → HCID 71268826, compound

https://huagongshe.com/reaction/1049968

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 71268944HCID 71268944—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 71268826HCID 71268826—

Reaction Steps

Tert-butyl 4-(4-(2-(4-(methoxycarbonyl)phenyl)-5-oxo-5,6-dihydropyrimido[4,5-d]pyridazin-4-ylamino)benzyl)piperazine-1-carboxylate (0.1 g, 0.175 mmol) was dissolved in dioxane.HCl (5 mL) and stirred at room temperature for 1.5 hours. The solid obtained was filtered and the residue washed with EtOAc and dried to give the desired product (40 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09382277B2
Source datasetuspto-grants-2016_07
ORD IDord-8aaf59ddb1b9416398f1e09f9a56650b
Source noteuspto-grants-2016_07