Methanesulfonyl chloride → HCID 90295545, compound

Participants

Reaction Steps

Using compound 4-((3R,3 aS)-3-(hydroxymethyl)-1-oxo-1,3,3a,4-tetrahydrobenzo[b]oxazolo[3,4-d][1,4]oxazin-7-yl)-3-oxopiperazin-1-carboxylic acid benzyl ester (0.946 g, 2.088 mmol), methylsulfonyl chloride (0.359 g, 3.13 mmol), and TEA (0.422 g, 4.18 mmol) as starting materials, preparation following the method as described in Example 1 (c) afforded white solid 0.916 g, yield: 82.52%.

Provenance & Evidence