HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → L-Alanine, phenylmethyl ester, hydrochloride (1:1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Nitrogen | HCID 947 | — |
| Reactant | BOC-L-Alanine benzyl ester | HCID 10972741 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | L-Alanine, phenylmethyl ester, hydrochloride (1:1) | HCID 12210893 | — |
Reaction Steps
Boc-Ala-OBn was dissolved in 4N HCl in dioxane (10 mL) and stirred for three hours at room temperature. The solvent was blown off under a stream of N2. The residue was placed under high vacuum for one hour. Re-dissolved in CH2Cl2 (50 mL) and rotovap dry. Repeat the drying circle for three times till the white powder forms.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388132B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-f1310d1d63a64cd29851716705ffebc6 |
| Source note | uspto-grants-2016_07 |