HRID1051132

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID21874893

5-Nitro-3-(trifluoromethyl)-2-pyridinecarbonitrile

C7H2F3N3O2

PRODUCTS

生成物

HCID13532246

5-Amino-3-(trifluoromethyl)pyridine-2-carbonitrile

C7H4F3N3

收率 91%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID23925

Iron

溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

A mixture of 5-nitro-3-(trifluoromethyl)pyridine-2-carbonitrile 22 and iron powder in acetic acid is heated. 5-amino-3-(trifluoromethyl)pyridine-2-carbonitrile, 8 is obtained in a yield of 91%.

WORKUP

后处理

temperatureis heated