反应详情

tert-butyl 3-(benzyloxy)azetidine-1-carboxylate 23 (1.0 μm) was taken into a round bottomed flask and was added methanolic-HCl (15 mL, 20%) and was stirred for 1 h at room temperature. After completion of the reaction (monitored by TLC), the solvent was removed under vacuum to get a white solid as a crude product. The crude product was washed with ethyl acetate repeatedly and then dried well to obtain compound 24 as a white solid (92%) and was used further without purification.

1. customAfter completion of the reaction (monitored by TLC)
2. customthe solvent was removed under vacuum
3. customto get a white solid as a crude product
4. washThe crude product was washed with ethyl acetate repeatedly
5. customdried well