Hydrochloric Acid → HCID 136969441, compound

Participants

Reaction Conditions

Reaction Steps

A reaction mixture solution was prepared by dissolving 1.97 g of ethyl [4-(methoxymethoxy)-3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-4-methyl-1,3-thiazole-5-carboxylate in 25 mL of 1,4-dioxane and adding 5.0 mL of 2 M hydrochloric acid was heated under stirring at 60° C. for 8 hours. After the reaction mixture solution was cooled to room temperature, the precipitated solid was filtered to obtain 1.49 g of ethyl 2-[4-hydroxy-3-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-4-methyl-1,3-thiazole-5-carboxylate.

Provenance & Evidence