HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminothiazole → 4-Imidazo[2,1-b]thiazol-6-ylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminothiazole | HCID 2155 | — |
| Reactant | HCID 17755522 | HCID 17755522 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-Imidazo[2,1-b]thiazol-6-ylbenzaldehyde | HCID 398284 | — |
Reaction Steps
0.7 g (2.1 mM) 4-(2-Bromo-acetyl)-benzaldehyde and 2-aminothiazole (2 eq) are stirred in 15 ml DMF at 90° C. for 6 h. The DMF is evaporated and the residue suspended in ethyl acetate over night. The desired product is collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09387204B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-5c5d00645c854e0ba2dc2b3cc74c1f9d |
| Source note | uspto-grants-2016_07 |