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HRID1051574

反应详情

EQUATION

反应方程式

HRID 1051574 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(F)c2c1CC[C@H](C)N2
HCID118075452

未命名化合物

结构：C[C@H]1CCc2c(ccc(Br)c2O)N1C(=O)C1CC1
HCID118075707

未命名化合物

2 次

PRODUCTS

生成物

1
结构：C[C@H]1CCc2c(O)c(Br)cc(F)c2N1C(=O)C1CC1
HCID118086471

未命名化合物

PROCEDURE

实验过程

(S)-(6-Bromo-8-fluoro-5-hydroxy-2-methyl-3,4-dihydroquinolin-1 (2H)-yl)(cyclopropyl)methanone was synthesized from (S)-8-fluoro-5-methoxy-2-methyl-1,2,3,4-tetrahydroquinoline according to the procedures described above for (2S)-6-bromo-1-cyclopropanecarbonyl-2-methyl-1,2,3,4-tetrahydroquinolin-5-ol (Intermediate 2, Steps 1a, 2a, and 3). MS (ESI, pos. ion) m/z 328, 330 [M+H]+.