Methanol → 4-(4-benzylphenylamino)-6-(2-(1-N-BOC-piperazin-4-yl)ethylamino)-1,7-naphthyridine-3-carbonitrile
Reaction equation
[C:28](=[O:29])([O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[N:35]1[CH2:36][CH2:37][N:38]([CH2:41][CH2:42][NH2:43])[CH2:39][CH2:40]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][cH:10][c:11]([NH:14][c:15]2[c:16]([C:26]#[N:27])[cH:17][n:18][c:19]3[cH:20][n:21][c:22]([F:25])[cH:23][c:24]23)[cH:12][cH:13]1.[CH2:71]1[O:72][CH2:73][CH2:74][CH2:75]1.[CH3:69][OH:70].[Cl:66][CH2:67][Cl:68].[F:44][c:45]1[cH:46][c:47]2[c:48]([n:49][cH:50]1)[n:51][cH:52][cH:53][cH:54]2.[F:55][c:56]1[cH:57][cH:58][c:59]2[c:60]([n:61][cH:62][cH:63][cH:64]2)[n:65]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[cH:9][cH:10][c:11]([NH:14][c:15]2[c:16]([C:26]#[N:27])[cH:17][n:18][c:19]3[cH:20][n:21][c:22]([NH:43][CH2:42][CH2:41][N:38]4[CH2:37][CH2:36][N:35]([C:28](=[O:29])[O:30][C:31]([CH3:32])([CH3:33])[CH3:34])[CH2:40][CH2:39]4)[cH:23][c:24]23)[cH:12][cH:13]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-50cbc88000ee4a00a2c2cb751e007ba9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…