HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-bromopyridine → Ethyl [(5-bromopyridin-2-yl)carbamothioyl]carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-bromopyridine | HCID 70622 | — |
| Reactant | Ethyl isothiocyanatoformate | HCID 85320 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Ethyl [(5-bromopyridin-2-yl)carbamothioyl]carbamate | HCID 59286274 | — |
Reaction Steps
Ethoxycarbonylisothiocyanate (16.7 g) was added to a stirred solution of 2-amino-5-brompyridine (20 g) in dioxane (200 mL). The mixture was stirred for 2 h at r.t. A white solid precipitated. Hexane (20 mL) was added and the white solid was collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388177B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-cd99124a9ea24b0a9acfe666ea2dcbab |
| Source note | uspto-grants-2016_07 |