HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Thiosulfate → HCID 83646766, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Thiosulfate | HCID 24477 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Methyl cyclohex-2-ene-1-carboxylate | HCID 11007985 | — |
| Reactant | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 83646766 | HCID 83646766 | — |
Reaction Steps
At 0° C., NBS (9.08 g, 51.0 mmol) was added to a soln. of methyl cyclohex-2-enecarboxylate (5.96 g, 42.5 mmol) [Bioorg. Med. Chem. 1999, 7, 1505-1511] in THF/H2O (500 mL, 9:1). The mixture was allowed to warm to RT and stirred for 2 h. Subsequently, aq. sat. Na2S2O3 and aq. sat. NaHCO3 were added and the mixture was conc. in vacuo.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388197B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-2409a8fdb9364332b5cfb69f3cc697b2 |
| Source note | uspto-grants-2016_07 |