HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine → N-(3-isopropylphenyl)-3-methyl-5-[2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Methylthio)-5,6,7,8-tetrahydropyrido[4,3-D]pyrimidine | HCID 55263670 | — |
| Reactant | 3-bromo-N-(3-isopropylphenyl)-5-methylbenzamide | HCID 86695860 | — |
| Product | N-(3-isopropylphenyl)-3-methyl-5-[2-(methylthio)-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]benzamide | HCID 86695862 | — |
Reaction Steps
In a manner similar to that described for Example 138, 2-(methylsulfanyl)-5,6,7,8-tetrahydropyrido[4,3-d]-pyrimidine and 3-bromo-N-(3-isopropylphenyl)-5-methylbenzamide were converted to the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388176B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-56840269c35e41d7b8ae4d5faf0798c8 |
| Source note | uspto-grants-2016_07 |