反应详情

温度

50 °C

To methyl 2-(3-acetyl-5-(benzyloxy)-1H-indazol-1-yl)acetate (3.70 g, 10.9 mmol) in THF (80 mL) was added Pd/C (10%, 400 mg). The reaction mixture was stirred at 50° C. overnight under a H2 atmosphere. Then was filtered over a pad of Celite and the residue washed with CH2Cl2. Solvents were removed under reduced pressure to give the title compound. MS (LC/MS): 248.9 [M+H]+, 271.0 [M+Na]+; tR (HPLC conditions e): 3.36 min.

1. filtrationThen was filtered over a pad of Celite
2. washthe residue washed with CH2Cl2
3. customSolvents were removed under reduced pressure