反应详情

A solution of tert-butyl 2-(3-cyano-5-methyl-1H-pyrazolo[3,4-c]pyridin-1-yl)acetate (250 mg, 0.92 mmol) in TFA (4 mL) was subjected to microwave irradiation at 140° C. for 90 min. The reaction mixture was concentrated in vacuo, the residual solid was suspended in MeOH and concentrated again in vacuo. MS: 235.0 [M+H]+; tR (HPLC conditions d): 0.24 min.

1. customirradiation at 140° C. for 90 min
2. concentrationThe reaction mixture was concentrated in vacuo
3. concentrationconcentrated again in vacuo
4. custom0.24 min.