HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 118433752, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | (S)-tert-Butyl (1-(4-oxo-3-phenyl-5-(phenylthio)-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl)carbamate | HCID 131736125 | — |
| Product | HCID 118433752 | HCID 118433752 | 95.6% |
Reaction Steps
(S)-tert-Butyl (1-(4-oxo-3-phenyl-5-(phenylthio)-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl)carbamate (190 mg, 0.41 mmol) was treated with trifluoroacetic acid (316 μl, 4.10 mmol) according to the method of Preparation 6 to obtain 142 mg (95% yield) of the title compound as a oil. Purity 95%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09388189B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-b8c5cba2c05240df9adfa308bca2c746 |
| Source note | uspto-grants-2016_07 |