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HRID1052425

反应详情

EQUATION

反应方程式

HRID 1052425 的结构方程式

REACTANTS

反应物

2
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：COc1cccc(Sc2ccn3nc([C@H](C)NC(=O)OC(C)(C)C)n(-c4ccccc4)c(=O)c23)c1
HCID131736152

未命名化合物

PRODUCTS

生成物

1
结构：COc1cccc(Sc2ccn3nc([C@H](C)N)n(-c4ccccc4)c(=O)c23)c1
HCID118433878

未命名化合物

收率 84.7%

PROCEDURE

实验过程

(S)-tert-Butyl (1-(5-((3-methoxyphenyl)thio)-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl)carbamate (154 mg, 0.31 mmol) was treated with trifluoroacetic acid (240 μl, 3.12 mmol) according to the method of Preparation 6 to obtain 103 mg (78% yield) of the title compound as an oil. Purity 92%.

WORKUP

后处理

  1. customaccording to the method of Preparation 6