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HRID1052429

反应详情

EQUATION

反应方程式

HRID 1052429 的结构方程式

REACTANTS

反应物

3
结构：Cl
HCID313

Hydrochloric Acid

ClH

结构：C1COCCO1
HCID31275

1,4-Dioxane

C4H8O2

结构：C[C@H](NC(=O)OC(C)(C)C)c1nn2ccc(Sc3ccccc3O)c2c(=O)n1-c1ccccc1
HCID131736153

未命名化合物

PRODUCTS

生成物

1
结构：C[C@H](N)c1nn2ccc(Sc3ccccc3O)c2c(=O)n1-c1ccccc1
HCID118433855

未命名化合物

收率 154.5%

PROCEDURE

实验过程

(S)-tert-Butyl (1-(5-((2-hydroxyphenyl)thio)-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl)carbamate (252 mg, 0.33 mmol) was treated with a solution of hydrochloric acid in dioxane (4M, 2 mL, 8 mmol) according to the method described in Preparation 1 to obtain 193 mg (99% yield) of the title compound. Purity 99%.

WORKUP

后处理

  1. customdescribed in Preparation 1