HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Phenyl pyrrolidine-3-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Phenyl pyrrolidine-2-carboxylate | HCID 15598566 | — |
| Reactant | 1-tert-Butyl 3-phenyl pyrrolidine-1,3-dicarboxylate | HCID 89873732 | — |
| Product | Phenyl pyrrolidine-3-carboxylate | HCID 69577543 | — |
Reaction Steps
The compound 25 was prepared according to the method described for compound 23 employing TFA (0.66 mL, 8.58 mmol) and compound 24 (500 mg, 1.71 mmol) to give white solid compound. The compound was used without further purification after solvent removal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09393306B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-0f001729c14f4ad6807ebbd1657c1e36 |
| Source note | uspto-grants-2016_07 |