HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 1-(3-Phenoxypropyl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Phenyl pyrrolidine-2-carboxylate | HCID 15598566 | — |
| Reactant | tert-Butyl 4-(3-phenoxypropyl)piperazine-1-carboxylate | HCID 131736284 | — |
| Product | 1-(3-Phenoxypropyl)piperazine | HCID 2760351 | — |
Reaction Steps
The compound 30 was prepared according to the method described for compound 23 employing TFA (6 mL) and compound 28 (550 mg, 1.72 mmol) to give white solid compound. The compound was used without further purification after solvent removal.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09393306B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-7469df9e5e3040b4a2be972c9df7fe97 |
| Source note | uspto-grants-2016_07 |